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Seroquel
Generic Seroquel ( Quetiapine )
Seroquel is an oral antipsychotic drug to treat major depressive disorder, schizophrenia and bipolar disorder.
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25 mg
30 丸
Seroquel
lei218.22
lei 181.84
lei 6.05 当たり ピル
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 0.00
25 mg
60 丸
Seroquel
lei349.18
lei 290.98
lei 4.87 当たり ピル
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 70.94
25 mg
90 丸
Seroquel
lei469.23
lei 391.01
lei 4.37 当たり ピル
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 151.42
25 mg
120 丸
Seroquel
lei561.99
lei 468.32
lei 3.91 当たり ピル
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 256.46
25 mg
180 丸
Seroquel
lei763.88
lei 636.56
lei 3.55 当たり ピル
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 450.17
25 mg
360 丸
Seroquel
lei1375.03
lei 1145.85
lei 3.18 当たり ピル
+ 無料の標準の航空サービス
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 1031.30
50 mg
30 丸
Seroquel
lei281.93
lei 236.41
lei 7.87 当たり ピル
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 0.00
50 mg
60 丸
Seroquel
lei454.72
lei 377.37
lei 6.28 当たり ピル
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 95.49
50 mg
90 丸
Seroquel
lei609.32
lei 509.24
lei 5.64 当たり ピル
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 200.53
50 mg
120 丸
Seroquel
lei732.10
lei 609.28
lei 5.09 当たり ピル
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 332.86
50 mg
180 丸
Seroquel
lei986.74
lei 823.00
lei 4.59 当たり ピル
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 589.32
100 mg
30 丸
Seroquel
lei413.80
lei 345.54
lei 11.50 当たり ピル
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 0.00
100 mg
60 丸
Seroquel
lei663.89
lei 554.71
lei 9.23 当たり ピル
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 136.42
100 mg
90 丸
Seroquel
lei900.35
lei 750.24
lei 8.32 当たり ピル
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 286.47
100 mg
120 丸
Seroquel
lei1082.23
lei 900.30
lei 7.50 当たり ピル
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 480.18
100 mg
180 丸
Seroquel
lei1455.10
lei 1214.06
lei 6.73 当たり ピル
+ 無料の標準の航空サービス
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 859.42
200 mg
30 丸
Seroquel
lei732.10
lei 609.28
lei 20.33 当たり ピル
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 0.00
200 mg
60 丸
Seroquel
lei1168.63
lei 973.06
lei 16.23 当たり ピル
+ 無料の標準の航空サービス
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 245.55
200 mg
90 丸
Seroquel
lei1573.33
lei 1309.55
lei 14.55 当たり ピル
+ 無料の標準の航空サービス
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 519.74
200 mg
120 丸
Seroquel
lei1887.09
lei 1573.29
lei 13.10 当たり ピル
+ 無料の標準の航空サービス
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 867.61
300 mg
30 丸
Seroquel
lei923.08
lei 768.43
lei 25.60 当たり ピル
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 0.00
300 mg
60 丸
Seroquel
lei1473.29
lei 1227.70
lei 20.46 当たり ピル
+ 無料の標準の航空サービス
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 308.30
300 mg
90 丸
Seroquel
lei1991.67
lei 1659.68
lei 18.46 当たり ピル
+ 無料の標準の航空サービス
+ パッケージ配達保険
+ 次の受注は10%の割引を
カートに追加
保存: lei 642.52

Common use

Seroquel is an oral antipsychotic (neuroleptic) medication used for treating schizophrenia and acute manic episodes associated with bipolar I disorder. It shows more affinity with serotonin receptors (5-HT2) than with dopamine receptors D1 and D2 in the brain. It also active toward the alpha 1 adrenoreceptor and less active toward alpha 2 adrenoreceptor. Duration of binding with 5-HT2-serotonin and D2 dopamine receptors is less than 12 hours. Mechanism of Quetiapine action is unknown. Though it is supposed that the therapeutic effect is mediated through a combination of dopamine type 2 (D2) and serotonin type 2 (5HT2) receptor antagonism. This medication is used to treat acute and chronic psychosis also ones in patients with schizophrenia.



Dosage and direction

Seroquel should be taken twice or thrice daily with or without food with a full glass of water. Swallo the tablet whole, do not crush or chew an extended-release tablet. Daily dose of four first therapeutic days is 50 mg, 100 mg (second day), 200 mg (third day), 300 mg (fourth day). Starting from the fourth day the dosage should be adjusted to the level of effective one (which can reach 750 mg daily). In patients with liver or kidney failure initial dose is 25 mg/day increased gradually by 25-50 mg till the effective dose is reached. Take exactly as prescribed by your physician and do not exceed the recommended dose.



Precautions

This medication affects ability to high concentration of attention so it may affect your ability to drive a car or operate machinery. Before to take Seroquel notify your doctor if you have liver or kidney disease, heart disease, high blood pressure, heart rhythm problems, heart attack or stroke in history, a history of low white blood cell counts, a thyroid disorder, high cholesterol or triglycerides, a personal or family history of diabetes, trouble swallowing, as you may need your dosage to be adjusted or pass special safety tests for this medication.



Contraindications

Hypersensitivity, pregnancy, breastfeeding. Seroquel should be used with cautiousness in patients with hypotension, epilepsy and epileptic seizures in history. Seroquel may contribute to development of heart failure, pneumonia, sudden death, in older adults with conditions caused by dementia.



Possible side effect

Seroquel antagonism of adrenergic a1 receptors may explain the orthostatic hypotension observed with this drug. Most common and frequent adverse effects of Seroquel are headache, agitation, dizziness, drowsiness, weight gain and stomach upset. Long term use of this medication may cause irreversible tardive dyskinesia, a neurologic disease which consists of involuntary movements of the jaw, lips, and tongue. Other side effects concern nervous system: headache, anxiety, fatigue, hostility, agitation, insomnia, tremors, convulsions, depression, neuroleptic malignant syndrome (hyperthermia, muscle rigidity, altered mental status, the lability of the autonomic nervous system increased activity of CPK). Adverse effects of Quetiapine for cardiovascular system are: tachycardia, prolongation of the interval QT. Dryness of the oral mucosa, nausea, vomiting, abdominal pain, diarrhea or constipation, increased activity of "liver" transaminases, pharyngitis, rhinitis may also appear. Allergic reactions such as skin rash, eosinophilia are also not excluded.



Drug interaction

Phenytoin (Dilantin) and thioridazine (Mellaril) decrease absorption of Seroquel in intestines and decrease its effects. Seroquel interacts with narcotic pain relievers, medications for hypertension interact with and their activities add: oxycodone and acetaminophen (Percocet, Roxicet, Tylox, Endocet), barbiturates, alprazolam (Xanax), clonazepam (Klonopin), ethanol, prazosin (Minipress) and terazosin (Hytrin). Toxicity of Quetiapine may increase if it is co-administered with the drugs able to influence work of cytochrome P450 which is responsible for metabolism of Seroquel, these drugs are: ketoconazole (Nizoral), itraconazole (Sporanox), fluconazole (Diflucan), erythromycin, clarithromycin (Biaxin), nefazodone (Serzone), verapamil (Calan, Isoptin, Verelan), diltiazem (Cardizem, Tiazac, Dilacor).



Missed dose

Take the missed dose as soon as you remember. If it is almost time of your next dose just skip the missed dose and return to your schedule. Do not double dose this medication to make up the missed dose.



Overdose

If you took too much of Seroquel you may experience such symptomes: extreme drowsiness, fast heart rate, feeling light-headed, or fainting. If you suppose that took too much for this medication seek for immediate medical help.



Storage

Store Seroquel at room temperature, 15-30 C (59-86 F) away from sunlight, moisture, children and pets.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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